IS EXPLORATION OF ALTERNATE IMMUNE PATHWAYS NEEDED IN HIDRADENITIS SUPPURATIVA? A CASE OF ATOPIC DERMATITIS AND CONCURRENT HIDRADENITIS SUPPURATIVA RESPONDING TO DUPILUMAB

Hidradenitis suppurativa (HS) is an inflammatory dermatosis associated with overactive T helper 1/T helper 17 (Th1/Th17) cells.HS has been effectively treated with biologic medications; however, many such biologics lack large randomized controlled trials.Only one such biologic, adalimumab, has been approved quest fryer by the US Food and Drug Admin

In this article the author read more analyzes the features of functioning of the Soviet ideologeme in the literature of emigrants in details.Much attention is given to the term "ideologeme", its characteristics and features.Criteria of differentiation of the terms "Sovietism" and "ideologeme" are considered.There is the analysis of changes in perce

Preserving an accurate cell count is crucial for maintaining homeostasis.Apical extrusion, a process in which redundant cells are eliminated by neighboring cells, plays a key role in this regard.Recent studies have revealed that apical extrusion can also be triggered in cells transformed by oncogenes, suggesting it may be a mechanism popularfilm.bl